The match kicks off at 15:00 tomorrow at Maiden Castle, and all donations will go to Sport in Action Zambia.
The First XI are looking to regroup for the national play-offs after narrowly missing out on the Premier North title.
The Saints are six points clear at the top of the Premier North with two fixtures to play.
With the BUCS season well underway, Will Jennings and Ella Jerman look at Team Durham's performance so far in various sports.
Coming off a two-week break after having their game against the Derby Braves postponed due to injury, and enjoying a scheduled by-week the following Sunday, it took longer than usual for the Saints to get into the game.
Having played seven games, the women’s team sit unambiguously top of the BUCS Northern Premier League, having won all seven and possessing a game in hand ahead of Northumbria, who currently lie two points behind.
The Saints recorded a convincing 20-0 win for their first victory of the regular season.